Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250135 | 0.81 | TP53 (0.41) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL5252394 | 0.81 | TP53 (0.41) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL2517186 | 0.81 | TP53 (0.41) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL2516227 | 0.81 | TP53 (0.41) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL2522593 | 0.77 | CYP2C9 (0.40) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL2518090 | 0.77 | UTS2R (0.40) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL5250217 | 0.77 | UTS2R (0.40) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL5252724 | 0.76 | TAS1R3 (0.40) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL2514792 | 0.76 | TAS1R3 (0.40) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 | |
| SCHEMBL15933111 | 0.75 | SLC6A9 (0.41) | CYP2C9CYP2D6SLC6A9SLC6A5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034949-B2 | Pyrrolidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-11 | — | — | US | disclosed |
| US-20070167440-A1 | Novel pyrrolidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167440-A1 | Novel pyrrolidine compound and a process for preparing the same | CNR1, CNR2, OPRD1 | CYP2C9 375/4885CYP2D6 549/4885SLC6A9 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.