Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 7/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.39 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25272648 | 0.87 | KIT (0.49) | PDGFRBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL30456407 | 0.87 | KIT (0.49) | PDGFRBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL25725389 | 0.86 | ALDH1A1 (0.47) | GRM5EGFRALDH1A1CYP2C19MAPK1 | |
| SCHEMBL30405798 | 0.85 | OPRD1 (0.43) | PDGFRBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL25630734 | 0.84 | CYP1A2 (0.42) | IP6K1IP6K3IP6K2EGFRALDH1A1 | |
| SCHEMBL25272457 | 0.84 | AKT1 (0.49) | PDGFRBAKT1ALDH1A1CYP2C19MAPK1 | |
| SCHEMBL25233084 | 0.83 | CYP1A2 (0.47) | IP6K1IP6K3IP6K2EGFRALDH1A1 | |
| SCHEMBL31501697 | 0.83 | CYP1A2 (0.47) | IP6K1IP6K3IP6K2EGFRALDH1A1 | |
| SCHEMBL30406387 | 0.82 | HTT (0.53) | PDGFRBJAK3EGFRAKT1ALDH1A1 | |
| SCHEMBL25281197 | 0.82 | HTT (0.53) | PDGFRBJAK3EGFRAKT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164175-A2 | PROTACS OF MALT1 | TEGID THERAPEUTICS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |