Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.37 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25725389 | 0.87 | ALDH1A1 (0.47) | CYP1A2CYP3A4CLK4ALDH1A1MEN1 | |
| SCHEMBL25229495 | 0.84 | PDGFRB (0.39) | CYP1A2CYP3A4CLK4ALDH1A1HIF1A | |
| SCHEMBL31501697 | 0.84 | CYP1A2 (0.47) | CYP1A2CYP3A4CLK4ALDH1A1MEN1 | |
| SCHEMBL25233084 | 0.84 | CYP1A2 (0.47) | CYP1A2CYP3A4CLK4ALDH1A1MEN1 | |
| SCHEMBL25630530 | 0.83 | PTK2 (0.50) | CYP1A2CYP3A4CLK4ALDH1A1MEN1 | |
| SCHEMBL25630561 | 0.82 | KIT (0.41) | CYP1A2CYP3A4CLK4ALDH1A1MEN1 | |
| SCHEMBL25272648 | 0.78 | KIT (0.49) | CYP1A2CYP3A4ALDH1A1USP2HPGD | |
| SCHEMBL30456407 | 0.78 | KIT (0.49) | CYP1A2CYP3A4ALDH1A1USP2HPGD | |
| SCHEMBL30405798 | 0.76 | OPRD1 (0.43) | CYP1A2CYP3A4ALDH1A1USP2HPGD | |
| SCHEMBL25725354 | 0.75 | EGFR (0.41) | CYP1A2CYP3A4CLK4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |