Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.43 |
| ▸ | USP2 | O75604 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25233084 | 1.00 | CYP1A2 (0.47) | CYP1A2CYP3A4CLK4HSD17B10HPGD | |
| SCHEMBL25725389 | 0.86 | ALDH1A1 (0.47) | CYP1A2CYP3A4CLK4HSD17B10HPGD | |
| SCHEMBL25630734 | 0.84 | CYP1A2 (0.42) | CYP1A2CYP3A4CLK4HSD17B10HPGD | |
| SCHEMBL25229495 | 0.83 | PDGFRB (0.39) | CYP1A2CYP3A4CLK4HSD17B10HPGD | |
| SCHEMBL25273633 | 0.81 | ALDH1A1 (0.51) | CYP1A2CYP3A4CLK4HSD17B10HPGD | |
| SCHEMBL25227852 | 0.80 | HTT (0.44) | CYP1A2CYP3A4CLK4HSD17B10HPGD | |
| SCHEMBL31501711 | 0.80 | HTT (0.44) | CYP1A2CYP3A4CLK4HSD17B10HPGD | |
| SCHEMBL25725354 | 0.78 | EGFR (0.41) | CYP1A2CYP3A4CLK4HPGDLMNA | |
| SCHEMBL25272648 | 0.77 | KIT (0.49) | CYP1A2CYP3A4HSD17B10HPGDALDH1A1 | |
| SCHEMBL30456407 | 0.77 | KIT (0.49) | CYP1A2CYP3A4HSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | BALA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | MLLT1, MEN1, BMI1 | CYP1A2 3937/4885CYP3A4 4263/4885CLK4 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.