SCHEMBL25232145

SCHEMBL25232145

CN1CCN(c2cc([C]=O)cc(C(F)(F)F)c2)CC1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.45
ALDH1A1 P00352 1/20 0.43
GALR3 O60755 1/20 0.41
DRD2 P14416 4/20 0.41
DRD3 P35462 4/20 0.41
SIRT6 Q8N6T7 1/20 0.41
MET P08581 1/20 0.40
DDR1 Q08345 1/20 0.39
ATM Q13315 1/20 0.38
DGAT1 O75907 1/20 0.38
SOAT1 P35610 1/20 0.38
KCNH2 Q12809 1/20 0.38
CSF1R P07333 2/20 0.37
LYN P07948 1/20 0.37
KIT P10721 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3525504 0.85 DRD2 (0.51) ADRB1ALDH1A1DRD2DRD3MET
SCHEMBL12968839 0.84 ADRB1 (0.61) ADRB1ALDH1A1GALR3SIRT6MET
SCHEMBL15077174 0.78 ADRB1 (0.54) ADRB1ALDH1A1GALR3SIRT6MET
SCHEMBL428031 0.78 ADRB1 (0.50) ADRB1ALDH1A1GALR3SIRT6MET
SCHEMBL18255830 0.78 ADRB1 (0.50) ADRB1ALDH1A1GALR3SIRT6MET
SCHEMBL273503 0.76 ADRA2C (0.53) ADRB1ALDH1A1SIRT6METDGAT1
SCHEMBL18277904 0.76 PHGDH (0.49) ADRB1ALDH1A1GALR3SIRT6MET
SCHEMBL24309491 0.76 ADRB1 (0.49) ADRB1ALDH1A1GALR3SIRT6MET
SCHEMBL13349313 0.76 ALDH1A1 (0.46) ADRB1ALDH1A1GALR3SIRT6MET
SCHEMBL502328 0.75 DDR1 (0.49) ADRB1ALDH1A1METDDR1CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096304-A1 ISOXAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF 한양대학교 에리카산학협력단 2023-06-01 WO disclosed