Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 9/20 | 0.47 |
| ▸ | TIPARP | Q7Z3E1 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20818174 | 0.82 | NR1H2 (0.46) | TRPC5TIPARP | |
| SCHEMBL25275764 | 0.82 | TRPC5 (0.60) | TRPC5TIPARPPOLBALDH1A1 | |
| SCHEMBL20817920 | 0.80 | TRPC5 (0.48) | TRPC5TIPARPPOLBALDH1A1 | |
| SCHEMBL20818595 | 0.76 | TRPC5 (0.74) | TRPC5TIPARPALDH1A1 | |
| SCHEMBL25230738 | 0.72 | TRPC5 (0.46) | TRPC5TIPARPPOLBALDH1A1 | |
| SCHEMBL20818546 | 0.69 | TRPC5 (0.49) | TRPC5TIPARPPOLBALDH1A1 | |
| SCHEMBL20818370 | 0.69 | TRPC5 (0.56) | TRPC5TIPARPPOLB | |
| SCHEMBL20818111 | 0.69 | TRPC5 (0.56) | TRPC5TIPARPPOLB | |
| SCHEMBL20817850 | 0.69 | TRPC5 (0.58) | TRPC5TIPARPPOLBALDH1A1 | |
| SCHEMBL20831227 | 0.68 | POLB (0.68) | TRPC5TIPARPPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | PDXK, ATP6V1B1, REN | TRPC5 1439/4885TIPARP 3091/4885POLB 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.