Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 3/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25232876 | 0.81 | KDM4C (0.33) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30460030 | 0.81 | KDM4C (0.33) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30544898 | 0.80 | NPC1 (0.36) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL25238670 | 0.80 | NPC1 (0.36) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL30740368 | 0.80 | TGFBR1 (0.44) | KDM4CNPC1RAB9AL3MBTL1TGFBR1 | |
| SCHEMBL25239936 | 0.78 | GABRA5 (0.33) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30460092 | 0.78 | NPC1 (0.41) | KDM4CNPC1RAB9ARXRAGRIN1 | |
| SCHEMBL25278645 | 0.77 | KDM4C (0.35) | KDM4CNPC1RAB9ACREBBP | |
| SCHEMBL25278970 | 0.77 | ABCB11 (0.34) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL22806839 | 0.77 | SLCO1B1 (0.41) | KDM4CNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109878-A1 | TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-06-22 | — | — | WO | disclosed |