Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.68 |
| ▸ | DRD3 | P35462 | 7/20 | 0.67 |
| ▸ | DRD2 | P14416 | 5/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31178362 | 1.00 | KCNA5 (0.68) | KCNA5DRD3DRD2ALOX15MEN1 | |
| SCHEMBL25732877 | 0.85 | ALOX15 (0.68) | ALOX15MEN1KMT2ANPSR1POLB | |
| SCHEMBL25732854 | 0.83 | MEN1 (0.74) | DRD2ALOX15MEN1KMT2ANPSR1 | |
| SCHEMBL25732875 | 0.83 | MAPK1 (0.72) | ALOX15MEN1KMT2ANPSR1HSD17B10 | |
| SCHEMBL31326931 | 0.83 | MAPK1 (0.72) | ALOX15MEN1KMT2ANPSR1HSD17B10 | |
| SCHEMBL31178342 | 0.83 | MEN1 (0.69) | DRD2ALOX15MEN1KMT2ANPSR1 | |
| SCHEMBL25280464 | 0.83 | MEN1 (0.69) | DRD2ALOX15MEN1KMT2ANPSR1 | |
| SCHEMBL25239701 | 0.82 | ALOX15 (0.63) | ALOX15MEN1KMT2ANPSR1POLB | |
| SCHEMBL31178349 | 0.82 | ALOX15 (0.63) | ALOX15MEN1KMT2ANPSR1POLB | |
| Hydrochloric Acid SCHEMBL11442449 | 0.81 | DRD2 (0.72) | KCNA5DRD3DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | SYMRISE AG (DE) | 2025-02-27 | — | — | US | disclosed |
| EP-4452941-A1 | ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023117119-A1 | ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME | SYMRISE AG (DE) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023117119-A1 | ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME | SYMRISE AG (DE) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | TAS2R5, TAS2R7, TAS2R8 | KCNA5 729/4885DRD3 1212/4885DRD2 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.