Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DCK | P27707 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805294 | 0.81 | RAB9A (0.38) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL17371365 | 0.79 | ALOX15 (0.57) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL10968197 | 0.79 | NUDT1 (0.41) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL6135340 | 0.78 | HPGD (0.40) | HASPINHPGDLMNAALDH1A1NPC1 | |
| SCHEMBL12656989 | 0.78 | NPC1 (0.40) | HASPINHPGDLMNAALDH1A1NPC1 | |
| SCHEMBL14834735 | 0.78 | KMT2A (0.41) | HASPINHPGDLMNAALDH1A1NPC1 | |
| SCHEMBL9956852 | 0.78 | NPC1 (0.58) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL14834351 | 0.77 | KDM1A (0.43) | HASPINHPGDLMNAALDH1A1NPC1 | |
| SCHEMBL7834805 | 0.77 | NUDT1 (0.41) | HASPINHPGDLMNAALDH1A1NPC1 | |
| SCHEMBL7563183 | 0.77 | KMT2A (0.38) | HPGDLMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109775-A1 | PYRIMIDINE-ANNULATED TRIAZOLE DERIVATIVES AND THEIR USE IN PLATELET AGGREGATION INHIBITION | BEIJING HONGHUI MEDITECH CO., LTD (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023108363-A1 | PYRIMIDINE-ANNULATED TRIAZOLE DERIVATIVES AND THEIR USE IN PLATELET AGGREGATION INHIBITION | BEIJING HONGHUI MEDITECH CO., LTD (CN) | 2023-06-22 | — | — | WO | disclosed |
| CN-107580596-A | For treating and preventing the new sulphur imido acyl group purinone compound and derivative of virus infection | 豪夫迈·罗氏有限公司 | 2018-01-12 | — | — | CN | disclosed |