Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.52 |
| ▸ | TTK | P33981 | 18/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25287907 | 0.82 | TTK (0.42) | TTK | |
| SCHEMBL25243633 | 0.81 | TYK2 (0.47) | TTK | |
| SCHEMBL25286881 | 0.80 | TTK (0.57) | LRRK2TTK | |
| SCHEMBL25284382 | 0.80 | HPGD (0.51) | — | |
| SCHEMBL25241012 | 0.79 | PSEN1 (0.41) | LRRK2TTK | |
| SCHEMBL25241385 | 0.79 | TTK (0.42) | TTK | |
| SCHEMBL25238174 | 0.79 | NPC1 (0.44) | TTK | |
| SCHEMBL25283961 | 0.79 | EGFR (0.48) | TTK | |
| SCHEMBL25289693 | 0.78 | S1PR1 (0.39) | TTK | |
| SCHEMBL25293421 | 0.77 | GAA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |