Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23001107 | 0.89 | TP53 (0.46) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL8952974 | 0.88 | DNM1 (0.44) | LCKPPARDZDHHC20ZDHHC2SPHK1 | |
| SCHEMBL5382087 | 0.88 | DNM1 (0.44) | LCKPPARDZDHHC20ZDHHC2SPHK1 | |
| SCHEMBL15056532 | 0.88 | DNM1 (0.44) | LCKPPARDZDHHC20ZDHHC2SPHK1 | |
| SCHEMBL7688203 | 0.88 | DNM1 (0.44) | LCKPPARDZDHHC20ZDHHC2SPHK1 | |
| SCHEMBL17231131 | 0.88 | DNM1 (0.44) | LCKPPARDZDHHC20ZDHHC2SPHK1 | |
| Sulfuric Acid SCHEMBL31188472 | 0.87 | TP53 (0.55) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| Hydrochloric Acid SCHEMBL28455833 | 0.86 | DNM1 (0.46) | LCKPPARDZDHHC20ZDHHC2SPHK1 | |
| Ammonia Solution, Strong SCHEMBL28736955 | 0.86 | DNM1 (0.42) | LCKPPARDZDHHC20ZDHHC2SPHK1 | |
| SCHEMBL18532757 | 0.85 | DNM1 (0.38) | TP53LCKPPARDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384325-B1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | BLUE CUBE IP LLC (US) | 2018-04-04 | — | — | EP | disclosed |
| US-8497387-B2 | Process for preparing divinylarene dioxides | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-07-30 | — | — | US | disclosed |
| EP-2384325-A1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | Dow Global Technologies LLC (US) | 2011-11-09 | — | — | EP | disclosed |
| US-20110251412-A1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | BLUE CUBE IP LLC | 2011-10-13 | — | — | US | disclosed |
| CN-102190607-A | Green synthesis method of pesticide weedicide intermediate ethylsulfonyl acetonitrile | UNIV BEIJING CHEMICAL | 2011-09-21 | — | — | CN | disclosed |
| WO-2010077483-A1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251412-A1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | HAO2, DBN1, PPOX | TP53 4194/4885LCK 4425/4885PPARD 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.