Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25233639 | 0.91 | USP30 (0.51) | USP30ACKR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25230167 | 0.87 | USP30 (0.49) | USP30ACKR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25237287 | 0.87 | USP30 (0.49) | USP30ACKR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25238874 | 0.87 | USP30 (0.49) | USP30ACKR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25233750 | 0.85 | PIN1 (0.53) | ACKR3CNR1PIN1CLK2LRRK2 | |
| SCHEMBL25206616 | 0.83 | CYP1A2 (0.49) | USP30ACKR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25238847 | 0.82 | HPGDS (0.57) | USP30ACKR3PIN1CYP1A2CYP3A4 | |
| SCHEMBL25245452 | 0.81 | CYP1A2 (0.47) | USP30ACKR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25510789 | 0.81 | HPGDS (0.49) | ACKR3CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL25551810 | 0.80 | HPGDS (0.51) | USP30ACKR3CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034127-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | UNIVERSITÉ PARIS CITÉ (FR) | 2025-01-30 | — | — | US | claimed |
| EP-4433162-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | Samsara Therapeutics Inc. (US) | 2024-09-25 | — | — | EP | claimed |
| CN-118647613-A | Autophagy inducing compounds and uses thereof, in particular for central nervous system diseases | 轮回治疗公司 | 2024-09-13 | — | — | CN | claimed |
| WO-2023089052-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | Samsara Therapeutics Inc. (US) | 2023-05-25 | — | — | WO | claimed |
| US-20250034127-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | UNIVERSITÉ PARIS CITÉ (FR) | 2025-01-30 | — | — | US | disclosed |
| EP-4183449-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034127-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | SQSTM1, TFEB, BECN1 | USP30 1478/4885ACKR3 2126/4885CNR1 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.