SCHEMBL25248703

SCHEMBL25248703

COc1cccc2[nH]nc(CCN(C)C)c12

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 3/20 0.57
▸ HTR2A P28223 6/20 0.43
▸ HTR7 P34969 4/20 0.43
▸ HTR1A P08908 3/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ TTK P33981 1/20 0.41
▸ HTR2C P28335 3/20 0.39
▸ HTR2B P41595 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30566011 1.00 HTR6 (0.57) HTR6HTR2AHTR7HTR1AKDM4E
SCHEMBL25292178 0.86 ALDH1A1 (0.45) HTR6HTR2AHTR7HTR1AKDM4E
SCHEMBL25251586 0.85 HTR6 (0.41) HTR6HTR2AKDM4EALDH1A1HPGD
SCHEMBL25249419 0.85 HTR6 (0.41) HTR6HTR2AHTR7HTR1AKDM4E
SCHEMBL30566020 0.85 HTR6 (0.41) HTR6HTR2AKDM4EALDH1A1HPGD
SCHEMBL30565927 0.82 HTR2A (0.55) HTR6HTR2AKDM4EALDH1A1HPGD
SCHEMBL25243365 0.82 HTR2A (0.55) HTR6HTR2AKDM4EALDH1A1HPGD
SCHEMBL26811444 0.82 HTR2A (0.62) HTR6HTR2AHTR1A
SCHEMBL31411452 0.81 HTR1A (0.59) HTR6HTR2AHTR7HTR1AHTR2C
SCHEMBL5335320 0.80 HTR2A (0.43) HTR6HTR2AALDH1A1HPGDTTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
US-20250163044-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-05-22 — — US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed
EP-4452979-A1 COMPOUNDS Psylo Pty Ltd (AU) 2024-10-30 — — EP disclosed
WO-2023218423-A1 INDAZOLES AND THEIR USE IN METHODS FOR TREATING 5-HT2 RESPONSIVE CONDITIONS ELEUSIS THERAPEUTICS US, INC. (US) 2023-11-16 — — WO disclosed
WO-2023115165-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2023115165-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB HTR6 54/4885HTR2A 94/4885HTR7 192/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB HTR6 54/4885HTR2A 94/4885HTR7 192/4885
US-20250163044-A1 COMPOUNDS NLN, SLC18A2, PYGB HTR6 54/4885HTR2A 94/4885HTR7 192/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB HTR6 54/4885HTR2A 94/4885HTR7 192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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