SCHEMBL25249334

SCHEMBL25249334

CC(C)(C)OC(=O)N1CCCC1Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 1/20 0.47
▸ USP30 Q70CQ3 1/20 0.43
▸ KDM1A O60341 1/20 0.39
▸ IRAK4 Q9NWZ3 1/20 0.39
▸ PDE8B O95263 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ IL1B P01584 2/20 0.38
▸ P2RX7 Q99572 1/20 0.38
▸ TSHR P16473 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ ALOX5AP P20292 1/20 0.37
▸ FEN1 P39748 1/20 0.37
▸ ATM Q13315 2/20 0.36
▸ HSD11B1 P28845 1/20 0.36
▸ FPR3 P25089 1/20 0.36
▸ FPR2 P25090 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29825268 1.00 FFAR1 (0.47) FFAR1USP30KDM1AIRAK4PDE8B
SCHEMBL26598642 0.94 FFAR1 (0.49) FFAR1USP30KDM1AIRAK4PDE8B
SCHEMBL9886012 0.87 FFAR1 (0.46) FFAR1USP30KDM1AIL1BP2RX7
SCHEMBL2795787 0.83 USP30 (0.50) FFAR1USP30KDM1AALDH1A1MEN1
SCHEMBL29339937 0.83 USP30 (0.50) FFAR1USP30KDM1AALDH1A1MEN1
SCHEMBL30175048 0.83 USP30 (0.50) FFAR1USP30KDM1AALDH1A1MEN1
SCHEMBL28116128 0.82 PDE8B (0.43) IRAK4PDE8BALDH1A1IL1BP2RX7
SCHEMBL15270775 0.82 PDE8B (0.43) IRAK4PDE8BALDH1A1IL1BP2RX7
SCHEMBL2799598 0.82 USP30 (0.51) FFAR1USP30KDM1A
SCHEMBL21055109 0.81 FFAR1 (0.48) FFAR1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-04-10 — — US disclosed
US-20250059188-A1 ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-02-20 — — US disclosed
EP-4452977-A1 ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2024-10-30 — — EP disclosed
EP-4452978-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2024-10-30 — — EP disclosed
WO-2023115142-A1 ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2023115142-A1 ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2023115150-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2023115150-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 FFAR1 1395/4885USP30 1167/4885KDM1A 857/4885
US-20250059188-A1 ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 FFAR1 950/4885USP30 2886/4885KDM1A 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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