Sugi Predict

Sugi Predict / Compounds / SCHEMBL25252302

SCHEMBL25252302

SCHEMBL25252302

CC(=O)/C=C(/c1ccccc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A1 P22736 1/20 0.58
▸ NR4A2 P43354 1/20 0.58
▸ NR4A3 Q92570 1/20 0.58
▸ CYP1A1 P04798 1/20 0.50
▸ MAOB P27338 1/20 0.50
▸ CYP1B1 Q16678 1/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ CES2 O00748 2/20 0.48
▸ CES1 P23141 2/20 0.48
▸ PDPK1 O15530 2/20 0.48
▸ SRD5A2 P31213 1/20 0.47
▸ GSK3B P49841 2/20 0.46
▸ KDR P35968 1/20 0.45
▸ HSD11B1 P28845 1/20 0.44
▸ P2RX1 P51575 1/20 0.44
▸ PTPN1 P18031 2/20 0.42
▸ TSHR P16473 2/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3945570 0.93 NR4A1 (0.61) NR4A1NR4A2NR4A3CYP1A1MAOB
SCHEMBL3945957 0.86 NR4A1 (0.62) NR4A1NR4A2NR4A3CYP1A1MAOB
SCHEMBL3945969 0.86 NR4A1 (0.62) NR4A1NR4A2NR4A3CYP1A1MAOB
SCHEMBL4863098 0.84 CES2 (0.50) CES2CES1TSHRCYP1A2CYP3A4
SCHEMBL27589809 0.82 MTNR1A (0.48) CES2CES1TSHRCYP1A2CYP3A4
SCHEMBL28385832 0.82 MTNR1A (0.48) CES2CES1TSHRCYP1A2CYP3A4
SCHEMBL27922016 0.82 MTNR1A (0.48) CES2CES1TSHRCYP1A2CYP3A4
SCHEMBL27498418 0.82 MTNR1A (0.48) CES2CES1TSHRCYP1A2CYP3A4
SCHEMBL27573431 0.82 MTNR1A (0.48) CES2CES1TSHRCYP1A2CYP3A4
SCHEMBL26147577 0.81 NR4A1 (0.64) NR4A1NR4A2NR4A3CYP1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122147-A1 ARYL CYCLOHEXANEDIONE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF ADEKA CORPORATION (JP) 2025-04-17 — — US disclosed
EP-4458807-A1 ARYL CYCLOHEXANEDIONE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF ADEKA CORPORATION (JP) 2024-11-06 — — EP disclosed
CN-118613467-A Arylcyclohexanedione derivatives and salts thereof, pest control agents containing the same and methods of use thereof 株式会社艾迪科 2024-09-06 — — CN disclosed
WO-2023127807-A1 ARYL CYCLOHEXANEDIONE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF 株式会社ADEKA 2023-07-06 — — WO disclosed
WO-2023127807-A1 ARYL CYCLOHEXANEDIONE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF 株式会社ADEKA 2023-07-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122147-A1 ARYL CYCLOHEXANEDIONE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF DDT, KEAP1, TYR NR4A1 1268/4885NR4A2 1478/4885NR4A3 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.