Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.67 |
| ▸ | PTGES | O14684 | 2/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.67 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254374 | 0.92 | ALOX5 (0.62) | ALOX5PTGESPPARGPLAAT3PLAAT5 | |
| SCHEMBL25296313 | 0.85 | ALOX5 (0.59) | ALOX5PTGESPPARGPLAAT3PLAAT5 | |
| SCHEMBL25302418 | 0.83 | PTGES (0.58) | ALOX5PTGESPPARGPLAAT3PLAAT5 | |
| SCHEMBL3251669 | 0.81 | CYP3A4 (0.64) | ALOX5PTGESPPARGPLAAT3PLAAT5 | |
| SCHEMBL25302980 | 0.80 | ALOX5 (0.65) | ALOX5PTGESPPARGALDH1A1POLB | |
| SCHEMBL25250978 | 0.80 | MAPT (0.56) | ALOX5PTGESPPARGPLAAT3PLAAT5 | |
| SCHEMBL25254297 | 0.80 | ALOX5 (0.64) | ALOX5PTGESPPARGALDH1A1POLB | |
| SCHEMBL25297025 | 0.76 | MEN1 (0.53) | ALOX5PTGESPPARGALDH1A1POLB | |
| SCHEMBL25257221 | 0.76 | ALOX5 (0.65) | ALOX5PTGESPPARGALDH1A1GAA | |
| SCHEMBL25302225 | 0.76 | CYP3A4 (0.53) | ALOX5PTGESPPARGPLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |