Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.64 |
| ▸ | PTGES | O14684 | 6/20 | 0.64 |
| ▸ | PPARG | P37231 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254429 | 0.93 | PPARG (0.60) | ALOX5PTGESPPARGPOLBPSEN1 | |
| SCHEMBL25253207 | 0.80 | ALOX5 (0.67) | ALOX5PTGESPPARGPOLBALDH1A1 | |
| SCHEMBL25260549 | 0.80 | PTGES (0.62) | ALOX5PTGESPPARGPOLBALDH1A1 | |
| SCHEMBL11495602 | 0.79 | KMT2A (0.51) | ALOX5PTGESPPARGPOLBALDH1A1 | |
| SCHEMBL11495603 | 0.79 | KMT2A (0.51) | ALOX5PTGESPPARGPOLBALDH1A1 | |
| SCHEMBL25250978 | 0.79 | MAPT (0.56) | ALOX5PTGESPPARGPOLBALDH1A1 | |
| SCHEMBL25296313 | 0.78 | ALOX5 (0.59) | ALOX5PTGESPPARGALDH1A1KDM4E | |
| SCHEMBL25302980 | 0.76 | ALOX5 (0.65) | ALOX5PTGESPPARGPOLBALDH1A1 | |
| SCHEMBL20914994 | 0.74 | AKR1B10 (0.69) | ALOX5ALDH1A1KDM4EGAA | |
| SCHEMBL30449408 | 0.74 | AKR1B10 (0.69) | ALOX5ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |