Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25250978 | 0.91 | MAPT (0.56) | ALOX5TRPV1GAAALDH1A1KDM4E | |
| SCHEMBL25296313 | 0.88 | ALOX5 (0.59) | ALOX5TRPV1ALDH1A1KDM4EMAPT | |
| SCHEMBL2931779 | 0.85 | HTR1A (0.57) | ALOX5TRPV1GAAALDH1A1KDM4E | |
| SCHEMBL19127373 | 0.85 | MAPT (0.55) | ALOX5GAAALDH1A1KDM4EHPGD | |
| SCHEMBL10635812 | 0.85 | HTR1A (0.57) | ALOX5TRPV1GAAALDH1A1KDM4E | |
| SCHEMBL25300688 | 0.85 | ALOX15 (0.54) | ALOX5TRPV1GAAALDH1A1KDM4E | |
| SCHEMBL10610974 | 0.83 | HTR1A (0.61) | ALOX5TRPV1ALDH1A1HPGDMAPT | |
| SCHEMBL19126962 | 0.83 | MAPT (0.52) | ALOX5GAAALDH1A1KDM4EHPGD | |
| SCHEMBL10608581 | 0.83 | HTR1A (0.61) | ALOX5TRPV1ALDH1A1HPGDMAPT | |
| SCHEMBL25257077 | 0.83 | MAPT (0.61) | ALOX5GAAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |