Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | CASP1 | P29466 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | CASP7 | P55210 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014910 | 0.73 | KDM4E (0.72) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL2522896 | 0.69 | CASP1 (0.62) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL2525573 | 0.69 | KDM4E (0.84) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL12043118 | 0.68 | ALDH1A1 (0.70) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL1445522 | 0.66 | KDM4E (0.69) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL16940596 | 0.66 | KDM4E (0.62) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL12043114 | 0.65 | KDM4E (0.64) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL12043094 | 0.65 | KDM4E (0.85) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL12043096 | 0.65 | MEN1 (0.81) | KDM4EALDH1A1CASP1KMT2ACASP7 | |
| SCHEMBL5133306 | 0.64 | KDM4E (0.55) | KDM4EALDH1A1CASP1KMT2ACASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999972-B2 | Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration | NEURONASCENT, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| US-20110319391-A1 | METHODS AND COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | NEURONASCENT, INC. | 2011-12-29 | — | — | US | disclosed |
| US-8039462-B2 | Alzheimer's disease, stroke, traumatic brain injury, and depression, neurodegenerative diseases; antidepressants; a phenyl thiourea or urea derivatives; promote cell proliferation of stem or progenitor cells | NEURONASCENT, INC. (US) | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319391-A1 | METHODS AND COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | DCX, BDNF, GAP43 | KDM4E 3732/4885ALDH1A1 874/4885CASP1 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.