Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.55 |
| ▸ | CASP1 | P29466 | 11/20 | 0.55 |
| ▸ | MEN1 | O00255 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | CASP7 | P55210 | 10/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522896 | 0.81 | CASP1 (0.62) | KDM4EALDH1A1CASP1MEN1KMT2A | |
| SCHEMBL5014910 | 0.72 | KDM4E (0.72) | KDM4EALDH1A1CASP1MEN1KMT2A | |
| SCHEMBL2529501 | 0.71 | ALDH1A1 (0.63) | KDM4EALDH1A1CASP1MEN1KMT2A | |
| SCHEMBL12262605 | 0.70 | ALDH1A1 (1.00) | KDM4EALDH1A1CASP1MEN1KMT2A | |
| SCHEMBL5133305 | 0.67 | MEN1 (0.51) | KDM4EALDH1A1CASP1MEN1KMT2A | |
| SCHEMBL17872075 | 0.66 | CSF1R (0.54) | KDM4EALDH1A1CASP1MEN1KMT2A | |
| SCHEMBL2490935 | 0.66 | KDM4E (0.43) | KDM4EALDH1A1TDP1MAPTRECQL | |
| SCHEMBL28120216 | 0.65 | HPGDS (0.56) | KDM4EALDH1A1CASP1MEN1KMT2A | |
| SCHEMBL9945363 | 0.65 | NQO1 (0.69) | KDM4EALDH1A1CASP1MEN1KMT2A | |
| SCHEMBL29232119 | 0.64 | RET (0.47) | KDM4EALDH1A1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937252-A2 | METHODS AND COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | Neuronascent, Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007035722-A2 | METHODS AND COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | NEURONASCENT, INC. (US) | 2007-03-29 | — | — | WO | disclosed |