Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25250978 | 0.93 | MAPT (0.56) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL25257221 | 0.85 | ALOX5 (0.65) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15263105 | 0.84 | ALOX15 (0.52) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16429426 | 0.84 | ALOX15 (0.52) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1893128 | 0.84 | ALOX15 (0.52) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL25302980 | 0.83 | ALOX5 (0.65) | MAPTTTRALOX5ALDH1A1KDM4E | |
| SCHEMBL25297025 | 0.82 | MEN1 (0.53) | ALOX5TUBB1ALDH1A1KDM4EGAA | |
| SCHEMBL10611064 | 0.80 | HTR1A (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19TUBB1 | |
| SCHEMBL25263708 | 0.80 | IGF1R (0.55) | MAPTGAAHPGDHTTMEN1 | |
| SCHEMBL25254374 | 0.79 | ALOX5 (0.62) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |