Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13342914 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNATSHRHPGDHTT | |
| SCHEMBL25300556 | 0.85 | HTR3E (0.55) | SMN1; SMN2LMNATSHRHPGDMAPK1 | |
| SCHEMBL13342918 | 0.84 | CYP1A2 (0.62) | SMN1; SMN2LMNATSHRHPGDHTT | |
| SCHEMBL13342919 | 0.83 | RAB9A (0.62) | SMN1; SMN2LMNATSHRHPGDNPC1 | |
| SCHEMBL22322367 | 0.81 | ALDH1A1 (0.40) | TSHRGAANPSR1KMT2AHTR3A | |
| SCHEMBL13342921 | 0.80 | MEN1 (0.53) | SMN1; SMN2LMNATSHRHPGDHTT | |
| SCHEMBL652306 | 0.80 | SMN1; SMN2 (0.77) | SMN1; SMN2LMNATSHRHPGDHTT | |
| SCHEMBL13342920 | 0.76 | MEN1 (0.72) | SMN1; SMN2TSHRHTTMAPK1NPSR1 | |
| SCHEMBL27627299 | 0.76 | ALDH1A1 (0.56) | SMN1; SMN2LMNANPC1NPSR1MEN1 | |
| SCHEMBL13368660 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNATSHRHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |