SCHEMBL25263172

SCHEMBL25263172

CC(C)c1nn(-c2ccccc2)c2c1cc(O)c1ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.42
▸ GAA P10253 1/20 0.42
▸ MAPK13 O15264 1/20 0.36
▸ MAPK12 P53778 1/20 0.36
▸ MAPK11 Q15759 1/20 0.36
▸ MAPK14 Q16539 1/20 0.36
▸ KCNJ6 P48051 2/20 0.36
▸ KCNJ5 P48544 2/20 0.36
▸ KCNJ3 P48549 2/20 0.36
▸ MAPK1 P28482 3/20 0.36
▸ RIPK1 Q13546 3/20 0.36
▸ KDM4E B2RXH2 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ PPARA Q07869 1/20 0.35
▸ MPO P05164 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ NT5E P21589 1/20 0.35
▸ LMNA P02545 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405633 1.00 ALDH1A1 (0.42) ALDH1A1GAAMAPK13MAPK12MAPK11
SCHEMBL25257359 0.81 MAPT (0.46) ALDH1A1GAAKDM4ESMN1; SMN2MPO
SCHEMBL29404909 0.81 MAPT (0.46) ALDH1A1GAAKDM4ESMN1; SMN2MPO
SCHEMBL25256531 0.80 MAPK1 (0.53) ALDH1A1MAPK1KDM4ESMN1; SMN2KMT2A
SCHEMBL29405164 0.80 MAPK1 (0.53) ALDH1A1MAPK1KDM4ESMN1; SMN2KMT2A
SCHEMBL31037105 0.77 NPC1 (0.44) ALDH1A1KDM4EMPOKMT2ALMNA
SCHEMBL25263813 0.76 MAPT (0.38) ALDH1A1GAAMAPK14MAPK1KDM4E
SCHEMBL31037057 0.76 MDM2 (0.43) ALDH1A1GAAMAPK14KDM4EMPO
SCHEMBL29405648 0.76 MAPT (0.38) ALDH1A1GAAMAPK14MAPK1KDM4E
SCHEMBL25301625 0.76 MAPT (0.46) ALDH1A1GAAKDM4EKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same LMITO THERAPEUTICS INC. (KR) 2026-03-10 — — US disclosed
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME LMITO THERAPEUTICS INC. (KR) 2024-02-01 — — US disclosed
EP-4212530-A1 IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME Lmito Therapeutics Inc. (KR) 2023-07-19 — — EP disclosed
CN-115956071-A Imidazoquinoline or benzindazolone compounds and intermediates for their preparation LMITO药业株式会社 2023-04-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME NQO1, NFE2L2, KEAP1 ALDH1A1 122/4885GAA 1904/4885MAPK13 1453/4885
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same NQO1, CBR1, NFE2L2 ALDH1A1 238/4885GAA 3693/4885MAPK13 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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