SCHEMBL25301625

SCHEMBL25301625

Oc1cc2c(-c3ccccc3)nn(-c3ccccc3)c2c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.46
▸ NPSR1 Q6W5P4 3/20 0.44
▸ GAA P10253 2/20 0.44
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ RXFP1 Q9HBX9 1/20 0.41
▸ PTGS2 P35354 3/20 0.41
▸ PTGS1 P23219 2/20 0.41
▸ ALOX5 P09917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404539 0.90 NPSR1 (0.46) MAPTNPSR1GAAMEN1KMT2A
SCHEMBL25258057 0.90 NPSR1 (0.46) MAPTNPSR1GAAMEN1KMT2A
SCHEMBL29405659 0.85 NPSR1 (0.41) MAPTNPSR1GAAMEN1KMT2A
SCHEMBL25256150 0.85 NPSR1 (0.41) MAPTNPSR1GAAMEN1KMT2A
SCHEMBL29405164 0.79 MAPK1 (0.53) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL25256531 0.79 MAPK1 (0.53) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL29405099 0.78 LMNA (0.58) MAPTGAAMEN1KMT2AALDH1A1
SCHEMBL25301864 0.78 LMNA (0.58) MAPTGAAMEN1KMT2AALDH1A1
SCHEMBL25258035 0.77 CYP11B2 (0.43) MAPTNPSR1GAAMEN1KMT2A
SCHEMBL29402177 0.77 CYP11B2 (0.43) MAPTNPSR1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same LMITO THERAPEUTICS INC. (KR) 2026-03-10 — — US disclosed
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME LMITO THERAPEUTICS INC. (KR) 2024-02-01 — — US disclosed
EP-4212530-A1 IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME Lmito Therapeutics Inc. (KR) 2023-07-19 — — EP disclosed
CN-115956071-A Imidazoquinoline or benzindazolone compounds and intermediates for their preparation LMITO药业株式会社 2023-04-11 — — CN disclosed
WO-2022039460-A1 IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME 주식회사 엘마이토테라퓨틱스 2022-02-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME NQO1, NFE2L2, KEAP1 MAPT 217/4885NPSR1 4198/4885GAA 1904/4885
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same NQO1, CBR1, NFE2L2 MAPT 1433/4885NPSR1 2859/4885GAA 3693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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