Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30448189 | 1.00 | NPSR1 (0.46) | NPSR1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14536979 | 0.80 | MAP4K4 (0.45) | ALDH1A1MEN1LMNANPC1RAB9A | |
| SCHEMBL31277424 | 0.80 | PSMD14 (0.46) | NPSR1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25221991 | 0.80 | PSMD14 (0.46) | NPSR1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3754852 | 0.78 | KMT2A (0.45) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL16381210 | 0.78 | MAPK14 (0.49) | NPSR1ALDH1A1KMT2ALMNANPC1 | |
| SCHEMBL11841693 | 0.76 | ALDH1A1 (0.44) | NPSR1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25610918 | 0.75 | JMJD6 (0.36) | ALDH1A1LMNAMAPT | |
| SCHEMBL25608550 | 0.74 | LIPG (0.41) | ALDH1A1MEN1KMT2ALMNAPKM | |
| SCHEMBL13240021 | 0.73 | L3MBTL1 (0.49) | NPSR1ALDH1A1LMNAPPARGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444309-A1 | PYRIMIDINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107603-A1 | PYRIMIDINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |