Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.47 |
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28509811 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1SMPD1 | |
| SCHEMBL28496824 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1SMPD1 | |
| SCHEMBL10433655 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1SMPD1 | |
| Zinc Ion SCHEMBL30564834 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1SMPD1 | |
| SCHEMBL2777489 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1SMPD1 | |
| Lithium Ion SCHEMBL30084326 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1SMPD1 | |
| SCHEMBL31531885 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1SMPD1 | |
| SCHEMBL6867199 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1SMPD1 | |
| SCHEMBL6231547 | 0.98 | FDPS (0.45) | FDPSGGPS1CES2CES1 | |
| SCHEMBL5502578 | 0.95 | CA1 (0.44) | FDPSGGPS1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697786-B2 | Grease composition | NIPPON GREASE CO., LTD. (JP) | 2023-07-11 | — | — | US | claimed |
| US-10266787-B2 | Grease composition | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-23 | — | — | US | claimed |
| US-6919301-B2 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2005-07-19 | — | — | US | claimed |
| US-20030176298-A1 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2003-09-18 | — | — | US | claimed |
| JP-11035963-A | — | — | None | — | — | JP | disclosed |
| US-20250059458-A1 | Polyurea/Calcium Sulfonate Complex Grease Composition for Use in Constant Velocity Joints | Lanxess specialty chemicals co ltd (CN) | 2025-02-20 | — | — | US | disclosed |
| EP-4457323-A1 | POLYUREA/CALCIUM SULFONATE COMPLEX GREASE COMPOSITION FOR USE IN CONSTANT VELOCITY JOINTS | Lanxess Specialty Chemicals Co., Ltd. (CN) | 2024-11-06 | — | — | EP | disclosed |
| CN-118401641-A | Polyurea/calcium sulfonate complex grease composition for use in constant velocity joints | 朗盛特殊化学品有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-116410813-A | Polyurea/calcium sulfonate complex grease composition for use in constant velocity joints | 朗盛特殊化学品有限公司 | 2023-07-11 | — | — | CN | disclosed |
| WO-2023125235-A1 | POLYUREA/CALCIUM SULFONATE COMPLEX GREASE COMPOSITION FOR USE IN CONSTANT VELOCITY JOINTS | LANXESS SPECIALTY CHEMICALS CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |
| CN-114302942-A | Steel wire rope | 日本润滑脂株式会社 | 2022-04-08 | — | — | CN | disclosed |
| CN-111960706-B | Modified inorganic powder material, preparation method and membrane material containing modified inorganic powder material | 北京艾科美特新材料开发有限公司 | 2021-08-10 | — | — | CN | disclosed |
| EP-1734102-A1 | LUBRICATING AGENT COMPOSITION AND REDUCTION GEAR USING THE COMPOSITION, AND MOTOR DRIVE POWER STEERING DEVICE USING THE REDUCTION GEAR | JTEKT Corporation (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-20050221996-A1 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| US-20050221997-A1 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| US-20050221999-A1 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| US-6919301-B2 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2005-07-19 | — | — | US | disclosed |
| US-20040186025-A1 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2004-09-23 | — | — | US | disclosed |
| US-20030176298-A1 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| JP-H1135963-A | LUBRICATING GREASE COMPOSITION | NIPPON KOUYU:KK | 1999-02-09 | — | — | JP | disclosed |