Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29225584 | 0.84 | MAOA (0.47) | HTR2BMAOAPOLBALDH1A1MAPT | |
| SCHEMBL28004757 | 0.80 | MAOA (0.54) | HTR2BMAOAPOLBALDH1A1MAPT | |
| SCHEMBL26982496 | 0.80 | CYP3A4 (0.44) | HTR2BMAOAPOLBALDH1A1MAPT | |
| SCHEMBL29225596 | 0.80 | HTR2B (0.40) | HTR2BMAOAPOLBALDH1A1MAPT | |
| SCHEMBL28004759 | 0.78 | MAOA (0.52) | HTR2BMAOAPOLBALDH1A1MAPT | |
| SCHEMBL30403300 | 0.77 | MAOA (0.56) | HTR2BMAOAPOLBALDH1A1MAPT | |
| SCHEMBL70000 | 0.75 | PNMT (0.52) | HTR2BMAOAALDH1A1MAPTKDM4E | |
| SCHEMBL1626149 | 0.72 | MAPT (0.61) | HTR2BMAOAPOLBALDH1A1MAPT | |
| SCHEMBL5543262 | 0.72 | MAOA (0.46) | HTR2BMAOAPOLBALDH1A1MAPT | |
| SCHEMBL21694436 | 0.72 | TDP2 (0.47) | HTR2BMAOAPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039128-B2 | Fluorene compound, organic light emitting device and display device using the fluorene compound | CANON KABUSHIKI KAISHA (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100072885-A1 | FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2010-03-25 | — | — | US | disclosed |
| WO-2008146825-A1 | FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100072885-A1 | FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND | ARL1, AFF1, AFF2 | HTR2B 2787/4885MAOA 511/4885POLB 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.