Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11682498 | 0.91 | LMNA (0.53) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL11029320 | 0.88 | ALDH1A1 (0.46) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL11682495 | 0.88 | LMNA (0.50) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL28274515 | 0.88 | CA12 (0.52) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL16215077 | 0.86 | LMNA (0.53) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL6537210 | 0.86 | LMNA (0.53) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL28693395 | 0.86 | LMNA (0.49) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL6536244 | 0.85 | POLB (0.51) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL6647621 | 0.83 | LMNA (0.57) | LMNANPC1RAB9ACA12CA9 | |
| SCHEMBL29083719 | 0.83 | KMT2A (0.46) | LMNANPC1RAB9ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039669-B2 | Catalytic metathesis of secondary amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-10-18 | — | — | US | claimed |
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | claimed |
| EP-0736181-A1 | AUTOMATED LEAD ASSAY | Abbott Laboratories (US) | 1996-10-09 | — | — | EP | claimed |
| WO-1995017679-A1 | AUTOMATED LEAD ASSAY | ABBOTT LABORATORIES (US) | 1995-06-29 | — | — | WO | claimed |
| CN-117866201-A | Nanocellulose-based photo-curing resin and preparation method thereof | 广东睿鹏材料科学有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-8039669-B2 | Catalytic metathesis of secondary amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-8039669-B2 | Catalytic metathesis of secondary amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-8039669-B2 | Catalytic metathesis of secondary amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | disclosed |
| US-4219626-A | Accelerators for radical polymerization reactions with initiators free from peroxide groups | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | NAAA, NAT1, NAT10 | LMNA 2979/4885NPC1 2288/4885RAB9A 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.