Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.56 |
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353336 | 0.97 | ADRB2 (0.59) | ADRB2PDE2AACHETDP1CHRNA7 | |
| SCHEMBL248672 | 0.97 | ADRB2 (0.59) | ADRB2PDE2AACHETDP1CHRNA7 | |
| SCHEMBL334558 | 0.97 | ADRB2 (0.59) | ADRB2PDE2AACHETDP1CHRNA7 | |
| Hydrochloric Acid SCHEMBL29064863 | 0.94 | ADRB2 (0.56) | ADRB2PDE2AACHETDP1CHRNA7 | |
| SCHEMBL30913871 | 0.90 | ADRB2 (0.52) | ADRB2PDE2AACHETDP1CHRNA7 | |
| SCHEMBL10801845 | 0.90 | ADRB2 (0.52) | ADRB2PDE2AACHETDP1CHRNA7 | |
| SCHEMBL1314596 | 0.85 | ADRB2 (0.72) | ADRB2PDE2ATDP1LMNAROCK2 | |
| SCHEMBL13448213 | 0.84 | NFE2L2 (0.50) | ADRB2PDE2AALOX5CA1 | |
| SCHEMBL21273605 | 0.84 | TEAD4 (0.56) | ADRB2PDE2AACHETDP1CA1 | |
| SCHEMBL21273606 | 0.84 | TEAD4 (0.56) | ADRB2PDE2AACHETDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109973-A1 | PEROVSKITE METAL HALIDE ZERO-DIMENSIONAL QUANTUM DOT COMPOSITE MATERIAL AND PREPARATION METHOD THEREFOR, AND USE OF ORGANIC AMINE SALT | 南开大学 | 2023-06-22 | — | — | WO | disclosed |
| CN-114149641-B | Perovskite metal halide zero-dimensional quantum dot/polymer composite material, preparation method thereof and application of organic amine salt | 南开大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114369453-A | Perovskite metal halide zero-dimensional quantum dot composite material, preparation method thereof and application of organic amine salt | 南开大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-114195650-A | Perovskite metal halide zero-dimensional quantum dot composite material, preparation method thereof and application of organic amine salt | 南开大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-114149641-A | Perovskite metal halide zero-dimensional quantum dot/polymer composite material, preparation method thereof and application of organic amine salt | 南开大学 | 2022-03-08 | — | — | CN | disclosed |