SCHEMBL353336

SCHEMBL353336

Cc1ccc([C@@H](C)N)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.59
ACHE P22303 6/20 0.47
TDP1 Q9NUW8 1/20 0.47
PDE2A O00408 1/20 0.46
CHRNA7 P36544 1/20 0.46
ALOX5 P09917 1/20 0.43
MAOA P21397 2/20 0.43
CA7 P43166 2/20 0.43
MAOB P27338 1/20 0.43
LMNA P02545 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
GBA1 P04062 1/20 0.36
ALDH1A1 P00352 1/20 0.36
BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334558 1.00 ADRB2 (0.59) ADRB2ACHETDP1PDE2ACHRNA7
SCHEMBL248672 1.00 ADRB2 (0.59) ADRB2ACHETDP1PDE2ACHRNA7
Bromide SCHEMBL25270751 0.97 ADRB2 (0.56) ADRB2ACHETDP1PDE2ACHRNA7
Hydrochloric Acid SCHEMBL29064863 0.97 ADRB2 (0.56) ADRB2ACHETDP1PDE2ACHRNA7
SCHEMBL30913871 0.92 ADRB2 (0.52) ADRB2ACHETDP1PDE2ACHRNA7
SCHEMBL10801845 0.92 ADRB2 (0.52) ADRB2ACHETDP1PDE2ACHRNA7
SCHEMBL1314596 0.87 ADRB2 (0.72) ADRB2TDP1PDE2ALMNAALDH1A1
SCHEMBL21273606 0.86 TEAD4 (0.56) ADRB2ACHETDP1PDE2ACA1
SCHEMBL13448213 0.86 NFE2L2 (0.50) ADRB2PDE2AALOX5CA1
SCHEMBL21273605 0.86 TEAD4 (0.56) ADRB2ACHETDP1PDE2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081786-A Schiff base optical switch material, preparation method thereof and static three-dimensional display system 安徽省东超科技有限公司 2025-06-03 CN claimed
CN-120040438-A Isoxazole antiparasitic agents Synthesis method of medicine lotirana 华南农业大学 2025-05-27 CN claimed
US-20250078176-A1 ENVIRONMENTAL ATTRIBUTES FOR NITROGEN CONTAINING CHEMICALS BASF SE (DE) 2025-03-06 US claimed
CN-118978481-A Photochromic Schiff base material, preparation method thereof and application thereof in three-dimensional imaging 安徽省东超科技有限公司 2024-11-19 CN claimed
CN-118435582-A Environmental attributes of nitrogen-containing chemicals 巴斯夫欧洲公司 2024-08-02 CN claimed
WO-2023117926-A1 ENVIRONMENTAL ATTRIBUTES FOR NITROGEN CONTAINING CHEMICALS BASF SE (DE) 2023-06-29 WO claimed
US-20220064111-A1 ENANTIOSELECTIVE SYNTHESIS OF BRIVARACETAM AND INTERMEDIATES THEREOF CLININVENT RESEARCH PVT. LTD. (IN) 2022-03-03 US claimed
CN-108658784-B Synthesis method of (R) -1- (4-methylphenyl) ethylamine 联化科技股份有限公司 2020-12-18 CN claimed
US-9458463-B2 Method for treatment of diabetes by a small molecule inhibitor for GRK5 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-10-04 US claimed
WO-2015022437-A1 INDOLINONE DERIVATIVES AS GRK5 MODULATORS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-02-19 WO claimed
EP-2098519-A1 Process for the synthesis of ramelteon and its intermediates Teva Pharmaceutical Industries Ltd. (IL) 2009-09-09 EP claimed
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-03-12 US claimed
US-20080090907-A1 Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine ONO PHARMACEUTICAL CO., LTD. (JP) 2008-04-17 US claimed
US-20070032658-A1 Production method of optically active dephenylalanine compounds AJINOMOTO CO., INC. (JP) 2007-02-08 US claimed
EP-1749816-A1 Production method of optically active diphenylalanine compounds Ajinomoto Co., Ltd. (JP) 2007-02-07 EP claimed
EP-1741697-A1 CRYSTAL COMPRISING (2R)-2-PROPYLOCTOIC ACID AND AMINE ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-10 EP claimed
US-7087778-B2 Process for producing benzoxazine derivative and production intermediate thereof DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-08-08 US claimed
US-20050027119-A1 Process for producing benzoxazine derivative and production intermediate thereof DAIICHI PHARMACEUTICAL CO., LTD. 2005-02-03 US claimed
EP-1211254-A1 PROCESS FOR THE PREPARATION OF BENZOXAZINE DERIVATIVES AND INTERMEDIATES THEREFOR DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2002-06-05 EP claimed
EP-1142892-A1 PROCESSES FOR THE PREPARATION OF NOVEL NAPHTHYRIDINE DERIVATIVES Nippon Kayaku Kabushiki Kaisha (JP) 2001-10-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090907-A1 Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine TAS2R5, FFAR2, HRH2 ADRB2 52/4885ACHE 3249/4885TDP1 3119/4885
US-20220064111-A1 ENANTIOSELECTIVE SYNTHESIS OF BRIVARACETAM AND INTERMEDIATES THEREOF CYP2B6, CYP3A4, CYP2C19 ADRB2 139/4885ACHE 554/4885TDP1 3709/4885
US-20070032658-A1 Production method of optically active dephenylalanine compounds TYR, PAH, DDC ADRB2 1338/4885ACHE 676/4885TDP1 3471/4885
US-20050027119-A1 Process for producing benzoxazine derivative and production intermediate thereof CYP4Z1, COASY, VAT1 ADRB2 2425/4885ACHE 733/4885TDP1 4260/4885
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES CYP2B6, UGT1A6, CYP2A6 ADRB2 1661/4885ACHE 254/4885TDP1 2771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.