Sugi Predict

Sugi Predict / Compounds / SCHEMBL334558

SCHEMBL334558

SCHEMBL334558

Cc1ccc([C@H](C)N)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ADRB2 P07550 1/20 0.59
▸ ACHE P22303 6/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ PDE2A O00408 1/20 0.46
▸ CHRNA7 P36544 1/20 0.46
▸ ALOX5 P09917 1/20 0.43
▸ MAOA P21397 2/20 0.43
▸ CA7 P43166 2/20 0.43
▸ MAOB P27338 1/20 0.43
▸ LMNA P02545 1/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ GBA1 P04062 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353336 1.00 ADRB2 (0.59) ADRB2ACHETDP1PDE2ACHRNA7
SCHEMBL248672 1.00 ADRB2 (0.59) ADRB2ACHETDP1PDE2ACHRNA7
Bromide SCHEMBL25270751 0.97 ADRB2 (0.56) ADRB2ACHETDP1PDE2ACHRNA7
Hydrochloric Acid SCHEMBL29064863 0.97 ADRB2 (0.56) ADRB2ACHETDP1PDE2ACHRNA7
SCHEMBL30913871 0.92 ADRB2 (0.52) ADRB2ACHETDP1PDE2ACHRNA7
SCHEMBL10801845 0.92 ADRB2 (0.52) ADRB2ACHETDP1PDE2ACHRNA7
SCHEMBL1314596 0.87 ADRB2 (0.72) ADRB2TDP1PDE2ALMNAALDH1A1
SCHEMBL21273606 0.86 TEAD4 (0.56) ADRB2ACHETDP1PDE2ACA1
SCHEMBL13448213 0.86 NFE2L2 (0.50) ADRB2PDE2AALOX5CA1
SCHEMBL21273605 0.86 TEAD4 (0.56) ADRB2ACHETDP1PDE2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES ZYDUS LIFESCIENCES LIMITED (IN) 2025-12-25 — — US claimed
EP-4565233-A1 TREATMENT FOR APLASTIC ANEMIA (AA) Zydus Lifesciences Limited (IN) 2025-06-11 — — EP claimed
CN-120081786-A Schiff base optical switch material, preparation method thereof and static three-dimensional display system 安徽省东超科技有限公司 2025-06-03 — — CN claimed
EP-4539934-A1 TREATMENT FOR GLOMERULAR DISEASES Zydus Lifesciences Limited (IN) 2025-04-23 — — EP claimed
CN-119119035-A RIPK1 kinase target inhibitor and preparation method and application thereof 中山大学 2024-12-13 — — CN claimed
CN-118978481-A Photochromic Schiff base material, preparation method thereof and application thereof in three-dimensional imaging 安徽省东超科技有限公司 2024-11-19 — — CN claimed
US-20240173314-A1 TREATMENT OF SICKLE CELL ANAEMIA ZYDUS LIFESCIENCES LTD. (IN) 2024-05-30 — — US claimed
CN-118084786-A Schiff base compound, preparation method and application thereof 安徽省东超科技有限公司 2024-05-28 — — CN claimed
CN-117660389-A Transaminase mutant and application thereof in preparation of chiral amine compounds 浙江容锐科技有限公司 2024-03-08 — — CN claimed
WO-2024028744-A1 TREATMENT FOR APLASTIC ANEMIA (AA) ZYDUS LIFESCIENCES LIMITED (IN) 2024-02-08 — — WO claimed
EP-1427727-B1 COMPOUNDS WHICH INHIBIT THE RELEASE OF INFLAMMATORY CYTOKINES PROCTER & GAMBLE (US) 2005-01-26 — — EP claimed
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-12-23 — — US claimed
EP-1485167-A1 1,2-DIHYDROPYRAZOL-3-ONES AS CYTOKINE MEDIATORS The Procter & Gamble Company (US) 2004-12-15 — — EP claimed
US-6821971-B2 FOR PROPHYALXIS OF RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, INFLAMMATORY BOWEL DISEASE (IBS), SEPTIC SHOCK, CARDIOPULMONARY DYSFUNCTION, ACUTE RESPIRATORY DISEASE, CACHEXIA THE PROCTER & GAMBLE COMPANY 2004-11-23 — — US claimed
EP-1427727-A1 COMPOUNDS WHICH INHIBIT THE RELEASE OF INFLAMMATORY CYTOKINES THE PROCTER & GAMBLE COMPANY (US) 2004-06-16 — — EP claimed
US-6677337-B2 RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, INFLAMMATORY BOWEL DISEASE, CACHEXIA, SEPTIC SHOCK, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS THE PROCTER & GAMBLE COMPANY 2004-01-13 — — US claimed
US-20030225082-A1 1,2-dihydropyrazol-3-ones which controls inflammatory cytokines PROCTER & GAMBLE COMPANY, THE 2003-12-04 — — US claimed
WO-2003080184-A1 1,2-DIHYDROPYRAZOL-3-ONES AS CYTOKINE MEDIATORS THE PROCTER & GAMBLE COMPANY (US) 2003-10-02 — — WO claimed
US-20030105084-A1 Compound which inhibit the release of inflammatory cytokines THE PROCTER & GAMBLE COMPANY 2003-06-05 — — US claimed
WO-2003024970-A1 COMPOUNDS WHICH INHIBIT THE RELEASE OF INFLAMMATORY CYTOKINES THE PROCTER & GAMBLE COMPANY (US) 2003-03-27 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105084-A1 Compound which inhibit the release of inflammatory cytokines IL1B, IL1A, TNF ADRB2 205/4885ACHE 757/4885TDP1 4565/4885
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 ADRB2 125/4885ACHE 1631/4885TDP1 4721/4885
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES SSB, GRN, ALB ADRB2 4535/4885ACHE 2327/4885TDP1 3306/4885
US-20030225082-A1 1,2-dihydropyrazol-3-ones which controls inflammatory cytokines IL1B, IL1A, IL1R1 ADRB2 407/4885ACHE 3874/4885TDP1 2819/4885
US-20240173314-A1 TREATMENT OF SICKLE CELL ANAEMIA HBG1, HBB, HBG2 ADRB2 1044/4885ACHE 2537/4885TDP1 4578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.