Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1090688 | 0.90 | ALDH1A1 (0.51) | MAPTALDH1A1MAPK1KMT2ATYMS | |
| SCHEMBL7162505 | 0.83 | TYMS (0.53) | MAPTALDH1A1MAPK1KMT2ATYMS | |
| SCHEMBL3519263 | 0.83 | MAPT (0.57) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| Ethylene SCHEMBL7162329 | 0.81 | TYMS (0.51) | MAPTALDH1A1MAPK1KMT2ATYMS | |
| SCHEMBL1025994 | 0.81 | KMT2A (0.44) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8615975 | 0.79 | MEN1 (0.55) | MAPK1MEN1KMT2ANPSR1MAOA | |
| SCHEMBL1025249 | 0.77 | HSD17B1 (0.45) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL28899149 | 0.75 | ALDH1A1 (0.66) | MAPTALDH1A1TYMSGRM5 | |
| SCHEMBL22028064 | 0.75 | ALDH1A1 (0.61) | MAPTALDH1A1MAPK1TYMSPKM | |
| SCHEMBL30997742 | 0.75 | ALDH1A1 (0.61) | MAPTALDH1A1MAPK1TYMSPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401496-A | Tetrahydronaphthalene, phenylcyclobutane and phenylcyclopentane analogs as RXFP1 agonists | 百时美施贵宝公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023114819-A1 | TETRALINE, PHENYLCYCLOBUTANE, AND PHENYLCYCLOPENTANE ANALOGS AS RXFP1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |