SCHEMBL25276995

SCHEMBL25276995

CCS(=O)(=O)c1cc(C2CC2)cnc1-c1nc2cc(S(=O)(=O)C(F)(F)F)ccc2o1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ UTRN P46939 3/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ AHR P35869 1/20 0.40
▸ HDAC6 Q9UBN7 1/20 0.40
▸ MAOB P27338 1/20 0.37
▸ SLC47A1 Q96FL8 1/20 0.37
▸ MAPT P10636 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ POLB P06746 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ HSPD1 P10809 1/20 0.34
▸ PTPN2 P17706 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29766681 1.00 UTRN (0.40) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL29543305 0.91 UTRN (0.39) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL27150966 0.91 UTRN (0.39) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL25418156 0.91 UTRN (0.35) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL25885601 0.90 UTRN (0.41) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL29543430 0.89 UTRN (0.38) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL27153037 0.89 UTRN (0.38) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL25885605 0.88 UTRN (0.38) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL19302015 0.85 UTRN (0.37) UTRNCYP1A2AHRHDAC6MAOB
SCHEMBL30989624 0.85 UTRN (0.43) UTRNCYP1A2AHRHDAC6MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144258-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-05-28 — — US claimed
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-05-08 — — US claimed
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-11-28 — — US claimed
US-20240315245-A1 INSECT AND ACARINA PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-09-26 — — US claimed
US-20240260577-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-08-08 — — US claimed
CN-117998986-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-05-07 — — CN claimed
US-20240138409-A1 INSECT AND ACARINA PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-05-02 — — US claimed
WO-2024085224-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE 住友化学株式会社 2024-04-25 — — WO claimed
CN-117320552-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2023-12-29 — — CN claimed
CN-116916751-A Insect and acarina pest control 先正达农作物保护股份公司 2023-10-20 — — CN claimed
US-20260144258-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-05-28 — — US disclosed
US-20260144258-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-05-28 — — US disclosed
US-20260144258-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-05-28 — — US disclosed
EP-4606796-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE Sumitomo Chemical Company, Limited (JP) 2025-08-27 — — EP disclosed
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-05-08 — — US disclosed
WO-2023203038-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-10-26 — — WO disclosed
CN-116916751-A Insect and acarina pest control 先正达农作物保护股份公司 2023-10-20 — — CN disclosed
WO-2023152340-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-08-17 — — WO disclosed
WO-2023105065-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-06-15 — — WO disclosed
WO-2023105064-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-06-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240138409-A1 INSECT AND ACARINA PEST CONTROL ACACA, ACAT2, CHIA UTRN 2986/4885CYP1A2 1246/4885AHR 3444/4885
US-20240260577-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL H1-2, H1-0, H1-3 UTRN 3937/4885CYP1A2 548/4885AHR 454/4885
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAT1 UTRN 1984/4885CYP1A2 809/4885AHR 1765/4885
US-20240315245-A1 INSECT AND ACARINA PEST CONTROL ACACA, ACAT2, CHIA UTRN 2976/4885CYP1A2 1166/4885AHR 3406/4885
US-20260144258-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE PDXK, PUM1, CTRL UTRN 3681/4885CYP1A2 565/4885AHR 1843/4885
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAA2 UTRN 2692/4885CYP1A2 490/4885AHR 1642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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