⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27888588 | 0.69 | TBXAS1 (0.34) | — | |
| SCHEMBL19945191 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL29055872 | 0.62 | KMT2A (0.36) | — | |
| SCHEMBL8525654 | 0.59 | — | — | |
| Succinic Acid SCHEMBL22129336 | 0.58 | BCHE (0.32) | — | |
| Pyrazine SCHEMBL9690748 | 0.58 | CRBN (0.43) | — | |
| SCHEMBL2053476 | 0.57 | — | — | |
| SCHEMBL11257472 | 0.57 | TBXAS1 (0.32) | — | |
| SCHEMBL27524722 | 0.55 | CRBN (0.60) | — | |
| SCHEMBL15045 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355018-A | Process for the preparation of temozolomide | 克里斯泰利亚化学药物产品有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118355018-A | Process for the preparation of temozolomide | 克里斯泰利亚化学药物产品有限公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2023102627-A1 | PROCESS FOR THE PREPARATION OF TEMOZOLOMIDE | CRISTÁLIA PRODUTOS QUÍMICOS FARMACÊUTICOS LTDA (BR) | 2023-06-15 | — | — | WO | disclosed |