Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875175 | 0.73 | TDP1 (0.68) | LMNATDP1NPC1RAB9AKMT2A | |
| SCHEMBL51601 | 0.73 | TDP1 (0.68) | LMNATDP1NPC1RAB9AKMT2A | |
| SCHEMBL11210177 | 0.70 | ALDH1A1 (0.49) | MAPTLMNATDP1KMT2AMEN1 | |
| SCHEMBL2652364 | 0.69 | LMNA (0.58) | LMNATDP1NPC1RAB9AKMT2A | |
| Ethylene Glycol SCHEMBL15661698 | 0.69 | ALDH1A1 (0.62) | LMNATDP1NPC1RAB9AKMT2A | |
| SCHEMBL25233109 | 0.68 | CHRNB2 (0.45) | MAPTLMNACHRNB2CHRNA5CHRNA7 | |
| SCHEMBL18862636 | 0.68 | MAPK1 (0.55) | MAPTLMNATDP1NPC1RAB9A | |
| SCHEMBL514540 | 0.67 | LMNA (0.60) | LMNATDP1NPC1RAB9AKMT2A | |
| SCHEMBL9817384 | 0.67 | TDP1 (0.59) | LMNATDP1NPC1RAB9AKMT2A | |
| SCHEMBL4570317 | 0.67 | TDP1 (0.59) | MAPTLMNATDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |