Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.38 |
| ▸ | CASP1 | P29466 | 8/20 | 0.38 |
| ▸ | CASP7 | P55210 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054410 | 0.87 | GBA1 (0.37) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL25284926 | 0.83 | KDM4E (0.45) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL30166472 | 0.83 | KDM4E (0.45) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL25278577 | 0.81 | KDM4E (0.40) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL30166327 | 0.81 | GPR119 (0.48) | MAPTLMNA | |
| SCHEMBL25238108 | 0.81 | GPR119 (0.48) | MAPTLMNA | |
| SCHEMBL24054344 | 0.80 | KDM4E (0.44) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL24053877 | 0.79 | KDM4E (0.40) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL25695425 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL25695335 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454529-B2 | Piperazine cyclic ureas | Sironax Ltd. (KY) | 2025-10-28 | — | — | US | disclosed |
| CN-115697991-B | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| CN-115697991-A | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454529-B2 | Piperazine cyclic ureas | RIPK1, RIPK3, RIPK4 | ALDH1A1 3602/4885HSD17B10 4253/4885HPGD 1224/4885 |
| US-20230203019-A1 | Piperazine Cyclic Ureas | RIPK1, RIPK3, RIPK4 | ALDH1A1 3602/4885HSD17B10 4253/4885HPGD 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.