SCHEMBL25285779

SCHEMBL25285779

Cc1cnc(C)c(CC(=O)Nc2ccc(-c3cnccn3)cn2)c1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
WNT3A P56704 14/20 0.61
PORCN Q9H237 6/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17317024 0.80 WNT3A (0.54) WNT3APORCN
SCHEMBL17675613 0.78 WNT3A (0.61) WNT3APORCN
SCHEMBL16649515 0.78 WNT3A (0.68) WNT3APORCN
SCHEMBL1723597 0.76 WNT3A (1.00) WNT3APORCN
SCHEMBL12331945 0.76 PORCN (0.73) WNT3APORCN
SCHEMBL17673081 0.76 PORCN (0.60) WNT3APORCN
SCHEMBL1723533 0.75 WNT3A (1.00) WNT3APORCN
SCHEMBL12303049 0.74 WNT3A (0.84) WNT3APORCN
SCHEMBL12303069 0.74 WNT3A (0.85) WNT3APORCN
SCHEMBL16649505 0.74 PORCN (0.59) WNT3APORCN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230201194-A1 COMBINATION COMPOSITIONS FOR IMMUNOTHERAPY CUREGENIX CORPORATION 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230201194-A1 COMBINATION COMPOSITIONS FOR IMMUNOTHERAPY WNT1, CTNNB1, WNT3 WNT3A 4/4885PORCN 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.