Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190771 | 0.95 | CA2 (0.42) | CA2SLC34A1MAPTLMNA | |
| SCHEMBL31178377 | 0.84 | CA2 (0.42) | CA2SLC34A1MAPTLMNA | |
| Zinc Ion SCHEMBL190454 | 0.84 | CA2 (0.42) | CA2SLC34A1MAPTLMNA | |
| SCHEMBL28412166 | 0.84 | CA2 (0.42) | CA2SLC34A1MAPTLMNA | |
| Potassium Ion SCHEMBL8018454 | 0.84 | — | — | |
| SCHEMBL2904505 | 0.84 | — | — | |
| Lithium Ion SCHEMBL31178484 | 0.84 | — | — | |
| SCHEMBL191367 | 0.84 | CA2 (0.42) | CA2SLC34A1MAPTLMNA | |
| SCHEMBL20211527 | 0.84 | CA2 (0.42) | CA2SLC34A1MAPTLMNA | |
| SCHEMBL30695083 | 0.84 | CA2 (0.42) | CA2SLC34A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4201991-A1 | RESIN COMPOSITION FOR POWDER LAMINATION SHAPING METHOD, POWDER, SHAPED ARTICLE MANUFACTURING METHOD, AND SHAPED ARTICLE | Mitsubishi Engineering-Plastics Corporation (JP) | 2023-06-28 | — | — | EP | disclosed |