SCHEMBL25286708

SCHEMBL25286708

O=CCCCc1nccs1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.40
SLC6A3 Q01959 3/20 0.35
CHRM2 P08172 2/20 0.35
CHRM1 P11229 2/20 0.35
CHRM3 P20309 2/20 0.35
HIF1A Q16665 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
NOS1 P29475 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DRD4 P21917 1/20 0.32
COPS5 Q92905 1/20 0.32
CYP2D6 P10635 1/20 0.31
PLA2G4A P47712 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1628173 0.88
Bromide SCHEMBL4938367 0.86 FDPS (0.41) FDPSSLC6A3CHRM2CHRM1CHRM3
SCHEMBL6997367 0.85 FDPS (0.38) FDPSSLC6A3CHRM2CHRM1CHRM3
SCHEMBL5846600 0.81 FDPS (0.36) FDPSSLC6A3CHRM2CHRM1CHRM3
SCHEMBL2000599 0.80 DRD4 (0.38) FDPSSLC6A3CHRM2CHRM1CHRM3
SCHEMBL1051788 0.78
SCHEMBL5544438 0.77 FDPS (0.37) FDPSSLC6A3CHRM2CHRM1CHRM3
SCHEMBL22519197 0.76 MEN1 (0.38) FDPSCYP2C19ALDH1A1TSHRCYP2D6
SCHEMBL8671012 0.76 FDPS (0.47) FDPSSLC6A3CHRM2CHRM1CHRM3
SCHEMBL2089907 0.76 FDPS (0.42) FDPSSLC6A3CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712948-A2 GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME Renagade Therapeutics Management Inc. (US) 2026-03-25 EP disclosed
US-20250313525-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2025-10-09 US disclosed
US-20250171438-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS AGIOS PHARMACEUTICALS, INC. 2025-05-29 US disclosed
US-12215068-B2 Constrained lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2025-02-04 US disclosed
WO-2024238828-A2 GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2024-11-21 WO disclosed
EP-4452928-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF Renagade Therapeutics Management Inc. (US) 2024-10-30 EP disclosed
US-20240067598-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2024-02-29 US disclosed
US-20240067598-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2024-02-29 US disclosed
US-20240067598-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2024-02-29 US disclosed
WO-2023122752-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313525-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP FDPS 984/4885SLC6A3 4289/4885CHRM2 4870/4885
US-12215068-B2 Constrained lipids and methods of use thereof SGMS1, SGMS2, LNPEP FDPS 984/4885SLC6A3 4289/4885CHRM2 4870/4885
US-20240067598-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP FDPS 984/4885SLC6A3 4289/4885CHRM2 4870/4885
US-20250171438-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS PAH, KDM8, PHF8 FDPS 656/4885SLC6A3 1247/4885CHRM2 2577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.