Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | APP | P05067 | 7/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | BACE1 | P56817 | 3/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.72 |
| ▸ | MMP9 | P14780 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | TOP2A | P11388 | 2/20 | 0.72 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.72 |
| ▸ | MAOA | P21397 | 2/20 | 0.72 |
| ▸ | MAOB | P27338 | 2/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Curcumin SCHEMBL25285963 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL25288205 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL25240986 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL25251023 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL25250829 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL25290694 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL25247326 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL25245838 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL25249730 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 | |
| Curcumin SCHEMBL15268518 | 1.00 | HTR1A (0.73) | HTR1AAPPMAPTBACE1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190937-A1 | IRON COMPLEXES OF ESTERIFIED DERIVATIVES OF NATURAL PRODUCTS, AND METHODS OF USE | CORNELL UNIVERSITY | 2023-06-22 | — | — | US | claimed |
| US-20230190937-A1 | IRON COMPLEXES OF ESTERIFIED DERIVATIVES OF NATURAL PRODUCTS, AND METHODS OF USE | CORNELL UNIVERSITY | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190937-A1 | IRON COMPLEXES OF ESTERIFIED DERIVATIVES OF NATURAL PRODUCTS, AND METHODS OF USE | SLC40A1, TFRC, HAMP | HTR1A 4466/4885APP 2733/4885MAPT 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.