SCHEMBL25288246

SCHEMBL25288246

CC(Oc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NS(=O)(=O)C(F)F)c1ccc(F)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 1/20 0.39
▸ LIPG Q9Y5X9 1/20 0.39
▸ CA1 P00915 6/20 0.36
▸ CA2 P00918 6/20 0.36
▸ CA9 Q16790 6/20 0.36
▸ CA12 O43570 1/20 0.36
▸ CA3 P07451 1/20 0.36
▸ CA4 P22748 1/20 0.36
▸ CA6 P23280 1/20 0.36
▸ CA5A P35218 1/20 0.36
▸ CA7 P43166 1/20 0.36
▸ CA14 Q9ULX7 1/20 0.36
▸ CA5B Q9Y2D0 1/20 0.36
▸ CYP19A1 P11511 2/20 0.33
▸ IDO1 P14902 1/20 0.32
▸ TDO2 P48775 1/20 0.32
▸ SLC6A4 P31645 1/20 0.32
▸ MKNK2 Q9HBH9 1/20 0.31
▸ AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24133485 1.00 LPL (0.39) LPLLIPGCA1CA2CA9
SCHEMBL30408224 1.00 LPL (0.39) LPLLIPGCA1CA2CA9
SCHEMBL25313255 1.00 LPL (0.39) LPLLIPGCA1CA2CA9
SCHEMBL25706906 0.91 CA1 (0.35) CA1CA2CA9CA12CA3
SCHEMBL31319099 0.91 CA1 (0.35) CA1CA2CA9CA12CA3
SCHEMBL31319041 0.90 CA1 (0.37) CA1CA2CA9CA12CA3
SCHEMBL25706852 0.90 CA1 (0.37) CA1CA2CA9CA12CA3
SCHEMBL25304140 0.88 LPL (0.39) LPLLIPGCA1CA2CA9
SCHEMBL25262119 0.88 LPL (0.39) LPLLIPGCA1CA2CA9
SCHEMBL25304609 0.88 LPL (0.39) LPLLIPGCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227429-A1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-07-20 — — US disclosed
WO-2023115150-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed
CN-115956070-A Sulfonamide compounds 阿纳克西斯制药股份有限公司 2023-04-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227429-A1 SULPHONAMIDE COMPOUNDS MLKL, RIPK3, CASP1 LPL 3971/4885LIPG 2963/4885CA1 740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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