SCHEMBL25304140

SCHEMBL25304140

CCS(=O)(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1OC(C)c1ccc(F)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 1/20 0.39
▸ LIPG Q9Y5X9 1/20 0.39
▸ CYP19A1 P11511 1/20 0.37
▸ LMNA P02545 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ CA1 P00915 3/20 0.36
▸ CA2 P00918 3/20 0.36
▸ CA9 Q16790 3/20 0.36
▸ CA12 O43570 1/20 0.36
▸ CA3 P07451 1/20 0.36
▸ CA4 P22748 1/20 0.36
▸ CA6 P23280 1/20 0.36
▸ CA5A P35218 1/20 0.36
▸ CA7 P43166 1/20 0.36
▸ CA14 Q9ULX7 1/20 0.36
▸ CA5B Q9Y2D0 1/20 0.36
▸ MRGPRX1 Q96LB2 7/20 0.35
▸ HIF1A Q16665 2/20 0.32
▸ AAK1 Q2M2I8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25262119 1.00 LPL (0.39) LPLLIPGCYP19A1LMNAHPGD
SCHEMBL25304609 1.00 LPL (0.39) LPLLIPGCYP19A1LMNAHPGD
SCHEMBL25299276 0.93 LPL (0.38) LPLLIPGCYP19A1CA1CA2
SCHEMBL25299275 0.93 LPL (0.38) LPLLIPGCYP19A1CA1CA2
SCHEMBL25313255 0.88 LPL (0.39) LPLLIPGCYP19A1CA1CA2
SCHEMBL30408224 0.88 LPL (0.39) LPLLIPGCYP19A1CA1CA2
SCHEMBL24133485 0.88 LPL (0.39) LPLLIPGCYP19A1CA1CA2
SCHEMBL25288246 0.88 LPL (0.39) LPLLIPGCYP19A1CA1CA2
SCHEMBL25902345 0.84 LPL (0.40) LPLLIPGHIF1AAAK1ESR2
SCHEMBL24133615 0.83 LPL (0.42) LPLLIPGLMNAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-03-06 — — US disclosed
WO-2023115149-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2023115149-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS MLKL, RIPK3, CASP9 LPL 3669/4885LIPG 2631/4885CYP19A1 4119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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