SCHEMBL25288286

SCHEMBL25288286

[CH2]CN1C(=O)C=C(c2ccccc2)C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RGS4 P49798 2/20 0.54
MAPT P10636 5/20 0.49
ALDH1A1 P00352 3/20 0.49
NPSR1 Q6W5P4 3/20 0.49
GAA P10253 2/20 0.49
CCR6 P51684 2/20 0.49
HPGD P15428 2/20 0.49
ALOX12 P18054 2/20 0.49
CACNA1B Q00975 2/20 0.49
APBA1 Q02410 2/20 0.49
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.43
HCRTR1 O43613 1/20 0.40
S1PR4 O95977 1/20 0.40
HSP90AA1 P07900 1/20 0.40
S1PR1 P21453 1/20 0.40
BACE1 P56817 3/20 0.39
DRD2 P14416 1/20 0.39
DRD3 P35462 1/20 0.39
MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6878003 0.85 RGS4 (0.57) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL7857789 0.81 RGS4 (0.54) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL27595467 0.81 RGS4 (0.54) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL7774092 0.81 RGS4 (0.58) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL1535501 0.81 RGS4 (0.58) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL5318341 0.81 RGS4 (0.50) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL9171007 0.80 RGS4 (0.79) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL9562575 0.79 RGS4 (0.51) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL11069254 0.79 CA12 (0.53) RGS4MAPTALDH1A1NPSR1GAA
SCHEMBL7857853 0.79 RGS4 (0.51) RGS4MAPTALDH1A1NPSR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118235090-A Photosensitive resin composition and color filter 株式会社力森诺科 2024-06-21 CN disclosed
WO-2023119900-A1 PHOTOSENSITIVE RESIN COMPOSITION AND COLOR FILTER 株式会社レゾナック 2023-06-29 WO disclosed