Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CCR6 | P51684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288286 | 0.85 | RGS4 (0.54) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL27595467 | 0.85 | RGS4 (0.54) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL7857789 | 0.85 | RGS4 (0.54) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL7774092 | 0.85 | RGS4 (0.58) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL1535501 | 0.85 | RGS4 (0.58) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL9171007 | 0.83 | RGS4 (0.79) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL9562575 | 0.82 | RGS4 (0.51) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL11069254 | 0.82 | CA12 (0.53) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL7857853 | 0.82 | RGS4 (0.51) | RGS4MAPTALDH1A1NPSR1GAA | |
| SCHEMBL5318341 | 0.80 | RGS4 (0.50) | RGS4MAPTALDH1A1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812311-B2 | APPLYING PRECURSORS HAVING ETHYLNYL GROUP; CROSSLINKER AND A SOLVENT ONTO A SURFACE TO FORM ELECTRICALLY INSULATING LAYER; REACTING ETHYNYL GROUP WITH REACTIVE GROUP IN CARBON-CARBON BOND FORMING REACTION AND REACTING; CROSSLINKING | HONEYWELL INTERNATIONAL INC. | 2004-11-02 | — | — | US | disclosed |
| WO-2001019889-A9 | HIGHLY STABLE PACKAGING SUBSTRATES AND BROMINATED INDANE DERIVATIVES | ALLIED SIGNAL INC (US) | 2002-10-03 | — | — | WO | disclosed |
| US-20020132053-A1 | Highly stable packaging substrates | HONEYWELL INTERNATIONAL, INC. | 2002-09-19 | — | — | US | disclosed |
| EP-1226201-A1 | HIGHLY STABLE PACKAGING SUBSTRATES AND BROMINATED INDANE DERIVATIVES | AlliedSignal Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| US-6346296-B1 | ETHYNYL GROUPS ON BACKBONES, CROSSLINKING IN SOLVENTS | ALLIEDSIGNAL INC. | 2002-02-12 | — | — | US | disclosed |
| WO-2001019889-A1 | HIGHLY STABLE PACKAGING SUBSTRATES AND BROMINATED INDANE DERIVATIVES | ALLIEDSIGNAL INC. (US) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020132053-A1 | Highly stable packaging substrates | AGO2, EED, SYNJ2 | RGS4 3968/4885MAPT 4241/4885ALDH1A1 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.