SCHEMBL5318341

SCHEMBL5318341

C=CCN1C(=O)C=C(c2ccccc2)C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RGS4 P49798 2/20 0.50
CASP3 P42574 1/20 0.46
ALDH1A1 P00352 9/20 0.45
GAA P10253 5/20 0.45
MAPT P10636 5/20 0.45
HPGD P15428 4/20 0.45
NPSR1 Q6W5P4 3/20 0.45
CCR6 P51684 2/20 0.45
ALOX12 P18054 2/20 0.45
CACNA1B Q00975 2/20 0.45
APBA1 Q02410 2/20 0.45
DRD2 P14416 2/20 0.43
SIGMAR1 Q99720 1/20 0.43
LMNA P02545 4/20 0.40
HTT P42858 2/20 0.40
POLB P06746 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
PKM P14618 2/20 0.39
MEN1 O00255 1/20 0.39
MITF O75030 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25288286 0.81 RGS4 (0.54) RGS4ALDH1A1GAAMAPTHPGD
SCHEMBL6878003 0.80 RGS4 (0.57) RGS4ALDH1A1GAAMAPTHPGD
SCHEMBL7774092 0.77 RGS4 (0.58) RGS4CASP3ALDH1A1GAAMAPT
SCHEMBL27595467 0.77 RGS4 (0.54) RGS4ALDH1A1GAAMAPTHPGD
SCHEMBL7857789 0.77 RGS4 (0.54) RGS4ALDH1A1GAAMAPTHPGD
SCHEMBL1535501 0.77 RGS4 (0.58) RGS4ALDH1A1GAAMAPTHPGD
SCHEMBL9171007 0.76 RGS4 (0.79) RGS4CASP3ALDH1A1GAAMAPT
SCHEMBL9562575 0.75 RGS4 (0.51) RGS4ALDH1A1GAAMAPTHPGD
SCHEMBL11069254 0.75 CA12 (0.53) RGS4ALDH1A1GAAMAPTHPGD
SCHEMBL7857853 0.75 RGS4 (0.51) RGS4ALDH1A1GAAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1514854-A Preparation of copolymer/polyolfine-rubber blends by reactive processing with phenol-aldehyde condensate 2004-07-21 CN claimed
EP-1399508-A2 COPOLYMER/POLYOL FINE-RUBBER BLENDS BY REACTIVE PROCESSING WITH PHENOL-ALDEHYDE CONDENSATE Bayer Aktiengesellschaft (DE) 2004-03-24 EP claimed
WO-2002098973-A2 COPOLYMER/POLYOL FINE-RUBBER BLENDS BY REACTIVE PROCESSING WITH PHENOL-ALDEHYDE CONDENSATE BAYER AKTIENGESELLSCHAFT (DE) 2002-12-12 WO claimed
WO-2000064978-A1 THERMOPLASTIC POLYKETONE MOULDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 2000-11-02 WO claimed
EP-0208790-A1 PROCESS FOR PRODUCING MALEIMIDE COPOLYMER, AND THERMOPLASTIC RESIN PREPARED BY USING SAID COPOLYMER MITSUBISHI RAYON CO., LTD. (JP) 1987-01-21 EP claimed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
EP-3541355-A1 MALODOR COUNTERACTANT COMPOSITION AND METHODS Bell Flavors And Fragrances, Inc. (US) 2019-09-25 EP disclosed
WO-2018094314-A1 MALODOR COUNTERACTANT COMPOSITION AND METHODS BELL FLAVORS & FRAGRANCES, INC. (US) 2018-05-24 WO disclosed
EP-1268664-B1 THERMOPLASTIC MOULDING MATERIALS BASED ON SPECIAL GRAFT RUBBER COMPONENTS INEOS ABS JERSEY LTD (GB) 2016-04-13 EP disclosed
EP-1098918-B1 THERMOPLASTIC MOULDING MATERIALS BASED ON HIGHLY EFFECTIVE GRAFTED RUBBER COMPONENTS LANXESS DEUTSCHLAND GMBH (DE) 2007-12-05 EP disclosed
US-7060751-B2 Graft polymers based on ethylene/α-olefin rubbers and process for their production BAYER AKTIENGESELLSCHAFT (DE) 2006-06-13 US disclosed
EP-0531848-A1 Process for preparation of graft rubbers with reduced formation of coagulate BAYER AG (DE) 1993-03-17 EP disclosed
EP-0253236-B1 PROCESS FOR THE PREPARATION OF A THERMOPLASTIC MOULDING MASS BAYER AG (DE) 1992-01-15 EP disclosed
US-4885337-A OF AT LEAST ONE GRAFT POLYMER ON RUBBER BASE; TOUGHNESS, HARDNESS, GLOSS; VEHICLE INTERIOR BAYER AKTIENGESELLSCHAFT (DE) 1989-12-05 US disclosed
EP-0234576-A1 Prostacyclin analogue, and blood circulation improving agent and anti-ulcer composition containing it as active ingredient SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-09-02 EP disclosed
US-4647652-A HYDROLYZED POLYVINYL ACETATE, CARBOXY ACID BAYER AKTIENGESELLSCHAFT (DE) 1987-03-03 US disclosed
EP-0208790-A1 PROCESS FOR PRODUCING MALEIMIDE COPOLYMER, AND THERMOPLASTIC RESIN PREPARED BY USING SAID COPOLYMER MITSUBISHI RAYON CO., LTD. (JP) 1987-01-21 EP disclosed
EP-0116330-B1 ABS MOULDING MASSES BAYER AG (DE) 1986-09-10 EP disclosed
EP-0116330-A1 ABS moulding masses BAYER AG (DE) 1984-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound TST, TMT1A, CTH RGS4 3934/4885CASP3 3645/4885ALDH1A1 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.