Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525203 | 0.88 | ALDH1A1 (0.37) | FFAR1TRPV4F2RAOC3 | |
| SCHEMBL2532856 | 0.86 | MEN1 (0.36) | HSD11B1F2RKAT6AKAT5AOC3 | |
| SCHEMBL2526409 | 0.86 | AOC3 (0.34) | F2RKAT6AKAT5AOC3 | |
| SCHEMBL2531737 | 0.86 | P2RX7 (0.42) | F2RP2RX7AOC3 | |
| SCHEMBL2529298 | 0.84 | FFAR1 (0.34) | FFAR1KAT6AKAT5 | |
| SCHEMBL2528539 | 0.84 | P2RX7 (0.38) | FFAR1F2RP2RX7 | |
| SCHEMBL2530277 | 0.84 | ALPL (0.38) | F2RKAT6AKAT5AOC3 | |
| SCHEMBL2528541 | 0.84 | MEN1 (0.37) | P2RX7 | |
| SCHEMBL2528064 | 0.82 | ALDH1A1 (0.39) | F2RAOC3 | |
| SCHEMBL2525209 | 0.81 | F2 (0.38) | HSD11B1F2RP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | FFAR1 60/4885HSD11B1 2306/4885TRPV4 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.