Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | RRM1 | P23921 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25786754 | 0.86 | NPC1 (0.55) | NPC1RAB9AMAPTL3MBTL1PHGDH | |
| SCHEMBL25243075 | 0.83 | MAPT (0.55) | NPC1RAB9AMAPTL3MBTL1PHGDH | |
| SCHEMBL25293638 | 0.80 | ALDH1A1 (0.53) | NPC1PDPK1CYTH3AKT1MAPT | |
| SCHEMBL25253611 | 0.79 | ALDH1A1 (0.57) | NPC1RAB9APDPK1CYTH3AKT1 | |
| SCHEMBL4346849 | 0.76 | ALDH1A1 (0.68) | NPC1RAB9AMAPTKMT2AHTT | |
| SCHEMBL5452586 | 0.75 | MAPT (0.65) | NPC1RAB9AMAPTL3MBTL1MEN1 | |
| SCHEMBL6815299 | 0.74 | ALDH1A1 (0.58) | NPC1RAB9AMAPTL3MBTL1MEN1 | |
| SCHEMBL25298861 | 0.74 | EPHX1 (0.61) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4347512 | 0.74 | KMT2A (0.62) | MAPTKMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL15347550 | 0.73 | MAPT (0.62) | NPC1RAB9AMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250100980-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2025-03-27 | — | — | US | disclosed |
| WO-2023121022-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | 이화여자대학교 산학협력단 | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250100980-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | LTB4R2, LTB4R, CYSLTR2 | NPC1 1534/4885RAB9A 4301/4885PDPK1 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.