Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25293231 | 0.86 | NPC1 (0.56) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL25243075 | 0.80 | MAPT (0.55) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL6815299 | 0.76 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL5452586 | 0.74 | MAPT (0.65) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL15347550 | 0.72 | MAPT (0.62) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL11373029 | 0.72 | NPC1 (0.70) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL6815123 | 0.71 | GAA (0.60) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL641132 | 0.70 | PHGDH (0.67) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL30462446 | 0.70 | MAPK1 (0.54) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL1314971 | 0.69 | MAPT (0.57) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121022-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | 이화여자대학교 산학협력단 | 2023-06-29 | — | — | WO | disclosed |