Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601401 | 0.78 | GPR84 (0.65) | GPR84MPOHTR1AHTR2AHTR2C | |
| SCHEMBL25257202 | 0.73 | MTNR1A (0.39) | MPOHTR1AHTR1DHTR1BHTR2B | |
| SCHEMBL25256346 | 0.69 | GPR84 (0.51) | GPR84 | |
| SCHEMBL5793206 | 0.66 | GPR84 (0.67) | GPR84MPOHTR1AHTR2AHTR2C | |
| SCHEMBL2015074 | 0.64 | HTR2A (0.44) | GPR84MPOHTR1DHTR2AHTR2C | |
| SCHEMBL9912222 | 0.64 | GPR84 (0.67) | GPR84HTR1AHTR1DHTR2AHTR2C | |
| SCHEMBL17024241 | 0.64 | CYP2A6 (0.58) | GPR84HTR1AHTR1DHTR2AHTR2C | |
| SCHEMBL24358682 | 0.63 | GPR84 (0.71) | GPR84MPOHTR1AHTR1DHTR2A | |
| SCHEMBL26674798 | 0.61 | GPR84 (0.49) | GPR84MPOHTR1AHTR1DHTR2A | |
| SCHEMBL4633747 | 0.61 | MPO (0.68) | GPR84MPOHTR1AHTR1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122093-A1 | REV-ERB AGONISTS FOR TH17-MEDIATED INFLAMMATORY DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-29 | — | — | WO | disclosed |