Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528245 | 0.89 | PTGS2 (0.40) | GPR88 | |
| SCHEMBL2529784 | 0.86 | BACE1 (0.38) | BACE1GPR88 | |
| SCHEMBL2529932 | 0.84 | L3MBTL1 (0.36) | BACE1 | |
| SCHEMBL2528452 | 0.83 | AOC3 (0.34) | — | |
| SCHEMBL2528244 | 0.83 | L3MBTL1 (0.38) | BACE1 | |
| SCHEMBL2529628 | 0.83 | ELANE (0.42) | BACE1GPR88 | |
| SCHEMBL2525051 | 0.82 | GPR88 (0.44) | BACE1GPR88 | |
| SCHEMBL2526825 | 0.82 | AOC3 (0.46) | GPR88 | |
| SCHEMBL2531067 | 0.82 | GPR88 (0.36) | BACE1GPR88 | |
| SCHEMBL2529783 | 0.81 | L3MBTL1 (0.35) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | BACE1 1634/4885GPR88 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.